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Faculty by Research Topic
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Enzymology, Nutrition, and Metabolism
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Gene Expression
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Macromolecular Synthesis, Assembly, and Localization
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Molecular Medicine
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Plant Sciences
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Proteomics, Genomics, and Combinatorial Chemistry
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Receptors & Signaling
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Structural and Chemical Biology
Enzymology, Nutrition, and Metabolism
Donald H. Burke (Molecular Microbiology & Immunology) –
emailRibozyme mechanism and evolution and the Origin of Life; antiviral nucleic acid aptamers and the molecular basis of drug resistant HIV-1.
David W. Emerich –
emailEnzymology, physiology and genomics of biological nitrogen fixation and related metabolic activities.
Mark Hannink –
emailThe BTB-Kelch substrate adaptor family in development, oncogenesis and neurodegeneration.
Gerald Hazelbauer –
emailTransmembrane receptors and sensory transduction in bacterial chemotaxis.
Dennis B. Lubahn –
emailBiochemical genetics and epigenetics of estrogens and related receptors.
Jan A. Miernyk (USDA) –
emailProtein targeting and folding in plants, organelle biogenesis, posttranslational modifications.
Brenda A. Peculis –
emailRNA processing, RNA stability, RNA turnover, RNA decapping enzymes, snoRNPs required for ribosome biogenesis.
Michael J. Petris –
emailThe regulation of metal nutrition and impacts on common human diseases.
Joseph C. Polacco –
emailNitrogen and nitric oxide metabolism in plants.
Douglas D. Randall –
emailMetabolism, signal transduction, protein kinases and phosphorylated proteins in plants.
Krishna K. Sharma (Ophthalmology) –
emailStructure-function of crystallins, role of ocular proteases and molecular basis for cataract development.
Grace Y. Sun –
emailNeurodegenerative diseases, Signal transduction, phospholipases A2, oxidative stress, anti-inflammatory and anti-oxidant botanical compounds
John J. Tanner (Chemistry) –
emailX-ray crystallography of proline metabolic enzymes, bacterial virulence proteins and anti-DNA antibodies; structural bioinformatics of protein-bound water; molecular dynamics simulations of biological molecules.
Jay J. Thelen –
emailProteomics and phosphoproteomics of seed development in oil seeds.
Peter A. Tipton –
emailMechanistic enzymology applied to agriculturally and medically important enzymes.
Judy D. Wall –
emailEnvironmental microbiology; bioremediation of toxic metal; genetics and biochemistry of sulfate-reducing bacteria.
Gary A. Weisman –
emailNucleotide receptors and signaling in inflammation, cardiovascular and autoimmune exocrine disease.
return to top Gene Expression
William R. Folk –
emailGene expression and DNA replication of DNA tumor viruses; plant biotechnology and medical use.
Thomas Guilfoyle –
emailTranscriptional control by auxins in plants; plant RNA polymerases.
Gretchen Hagen –
emailControl of gene expression by plant growth regulators.
Mark Hannink –
emailThe BTB-Kelch substrate adaptor family in development, oncogenesis and neurodegeneration.
Dennis B. Lubahn –
emailBiochemical genetics and epigenetics of estrogens and related receptors.
Mark E. Martin –
emailTranscriptional control in mitochondrial biogenesis and oxidative stress.
Bruce A. McClure –
emailCell-cell interactions in pollen recognition and rejection.
Brenda A. Peculis –
emailRNA processing, RNA stability, RNA turnover, RNA decapping enzymes, snoRNPs required for ribosome biogenesis.
Michael J. Petris –
emailThe regulation of metal nutrition and impacts on common human diseases.
Charlotte L. Phillips –
emailCollagen in inherited and acquired diseases of bone and kidney; matrix metalloproteinases; medical genetics.
Joseph C. Polacco –
emailNitrogen and nitric oxide metabolism in plants.
R. Michael Roberts (Animal Science) –
emailReproductive biology: signaling between conceptus and uterus; stem cells.
Gary Stacey (Plant Pathology) –
emailFunctional genomics of plant-microbe interactions and plant development.
Richard Tsika –
emailTranscriptional regulation in striated muscle during development, activity, and stress; transgenic mouse models.
Gary A. Weisman –
emailNucleotide receptors and signaling in inflammation, cardiovascular and autoimmune exocrine disease.
Shuqun Zhang –
emailMAP kinases and signaling in plant defense responses.
return to top Macromolecular Synthesis, Assembly, and Localization
Lesa J. Beamer –
emailStructural biology: X-ray crystallography of medically important proteins.
Donald H. Burke (Molecular Microbiology & Immunology) –
emailRibozyme mechanism and evolution and the Origin of Life; antiviral nucleic acid aptamers and the molecular basis of drug resistant HIV-1.
Shi-jie Chen (Physics) –
emailPredicting RNA structures and structural changes; Computational studies of RNA thermal stability and folding kinetics.
William R. Folk –
emailGene expression and DNA replication of DNA tumor viruses; plant biotechnology and medical use.
Thomas Guilfoyle –
emailTranscriptional control by auxins in plants; plant RNA polymerases.
Mark Hannink –
emailThe BTB-Kelch substrate adaptor family in development, oncogenesis and neurodegeneration.
Gerald Hazelbauer –
emailTransmembrane receptors and sensory transduction in bacterial chemotaxis.
Antje Heese –
emailMembrane trafficking in plant innate immunity.
Bruce A. McClure –
emailCell-cell interactions in pollen recognition and rejection.
Jan A. Miernyk (USDA) –
emailProtein targeting and folding in plants, organelle biogenesis, posttranslational modifications.
Scott C. Peck –
emailProteomics of protein phosphorylation and protein kinases; signaling and secretion during host-pathogen interactions.
Brenda A. Peculis –
emailRNA processing, RNA stability, RNA turnover, RNA decapping enzymes, snoRNPs required for ribosome biogenesis.
Michael J. Petris –
emailThe regulation of metal nutrition and impacts on common human diseases.
Charlotte L. Phillips –
emailCollagen in inherited and acquired diseases of bone and kidney; matrix metalloproteinases; medical genetics.
Linda RandallMolecular chaperones in protein export; analysis of protein-protein interactions.
Krishna K. Sharma (Ophthalmology) –
emailStructure-function of crystallins, role of ocular proteases and molecular basis for cataract development.
Chun Tang –
emailSpatial and temporal characterization of macromolecular dynamics involved in protein complexes and signaling pathways
Richard Tsika –
emailTranscriptional regulation in striated muscle during development, activity, and stress; transgenic mouse models.
Steven R. Van Doren –
emailStructural biology: NMR investigations of protein structure, dynamics and protein-protein interactions, particularly proteins important in inflammatory diseases.
Gary A. Weisman –
emailNucleotide receptors and signaling in inflammation, cardiovascular and autoimmune exocrine disease.
Shuqun Zhang –
emailMAP kinases and signaling in plant defense responses.
return to top Molecular Medicine
Lesa J. Beamer –
emailStructural biology: X-ray crystallography of medically important proteins.
Donald H. Burke (Molecular Microbiology & Immunology) –
emailRibozyme mechanism and evolution and the Origin of Life; antiviral nucleic acid aptamers and the molecular basis of drug resistant HIV-1.
Susan L. Deutscher –
emailCombinatorial biology applied to cancer detection and therapy.
Laurie Erb –
emailMolecular studies of nucleotide receptors.
William R. Folk –
emailGene expression and DNA replication of DNA tumor viruses; plant biotechnology and medical use.
Kent Gates (Chemistry) –
emailMechanisms of DNA damage by synthetic and naturally occurring antitumor agents, toxins, and mutagens.
Mark Hannink –
emailThe BTB-Kelch substrate adaptor family in development, oncogenesis and neurodegeneration.
Michael Henzl –
emailBiophysical characterization of EF-hand calcium-binding proteins; protein-ligand interactions.
Dennis B. Lubahn –
emailBiochemical genetics and epigenetics of estrogens and related receptors.
Mark E. Martin –
emailTranscriptional control in mitochondrial biogenesis and oxidative stress.
Thomas P. Mawhinney –
emailCarbohydrates in cancer and bacterial infection; cancer prevention and treatment; host-pathogen interactions in cystic fibrosis; analytical methodologies.
Valeri Mossine –
emailCarbohydrates and cancer.
Brenda A. Peculis –
emailRNA processing, RNA stability, RNA turnover, RNA decapping enzymes, snoRNPs required for ribosome biogenesis.
Michael J. Petris –
emailThe regulation of metal nutrition and impacts on common human diseases.
Charlotte L. Phillips –
emailCollagen in inherited and acquired diseases of bone and kidney; matrix metalloproteinases; medical genetics.
Thomas P. Quinn –
emailCancer diagnostics, radiopharmaceutical imaging and therapy; cell and molecular imaging.
R. Michael Roberts (Animal Science) –
emailReproductive biology: signaling between conceptus and uterus; stem cells.
Frank J. Schmidt –
emailCombinatorial chemistry of RNA and antimicrobial peptides; the prebiotic RNA world.
Cheikh Seye –
emailNucleotide receptor signaling and cardiovascular disease.
Krishna K. Sharma (Ophthalmology) –
emailStructure-function of crystallins, role of ocular proteases and molecular basis for cataract development.
Grace Y. Sun –
emailNeurodegenerative diseases, Signal transduction, phospholipases A2, oxidative stress, anti-inflammatory and anti-oxidant botanical compounds
Peter A. Tipton –
emailMechanistic enzymology applied to agriculturally and medically important enzymes.
Richard Tsika –
emailTranscriptional regulation in striated muscle during development, activity, and stress; transgenic mouse models.
Steven R. Van Doren –
emailStructural biology: NMR investigations of protein structure, dynamics and protein-protein interactions, particularly proteins important in inflammatory diseases.
Wynn A. Volkert (Radiology) –
emailRadiopharmaceuticals for therapy and imaging; nuclear medicine.
Gary A. Weisman –
emailNucleotide receptors and signaling in inflammation, cardiovascular and autoimmune exocrine disease.
return to top Plant Sciences
David W. Emerich –
emailEnzymology, physiology and genomics of biological nitrogen fixation and related metabolic activities.
William R. Folk –
emailGene expression and DNA replication of DNA tumor viruses; plant biotechnology and medical use.
Thomas Guilfoyle –
emailTranscriptional control by auxins in plants; plant RNA polymerases.
Gretchen Hagen –
emailControl of gene expression by plant growth regulators.
Antje Heese –
emailMembrane trafficking in plant innate immunity.
Bruce A. McClure –
emailCell-cell interactions in pollen recognition and rejection.
Jan A. Miernyk (USDA) –
emailProtein targeting and folding in plants, organelle biogenesis, posttranslational modifications.
Scott C. Peck –
emailProteomics of protein phosphorylation and protein kinases; signaling and secretion during host-pathogen interactions.
Joseph C. Polacco –
emailNitrogen and nitric oxide metabolism in plants.
Douglas D. Randall –
emailMetabolism, signal transduction, protein kinases and phosphorylated proteins in plants.
Gary Stacey (Plant Pathology) –
emailFunctional genomics of plant-microbe interactions and plant development.
Jay J. Thelen –
emailProteomics and phosphoproteomics of seed development in oil seeds.
Steven R. Van Doren –
emailStructural biology: NMR investigations of protein structure, dynamics and protein-protein interactions, particularly proteins important in inflammatory diseases.
Shuqun Zhang –
emailMAP kinases and signaling in plant defense responses.
return to top Proteomics, Genomics, and Combinatorial Chemistry
Donald H. Burke (Molecular Microbiology & Immunology) –
emailRibozyme mechanism and evolution and the Origin of Life; antiviral nucleic acid aptamers and the molecular basis of drug resistant HIV-1.
Susan L. Deutscher –
emailCombinatorial biology applied to cancer detection and therapy.
Dwayne A. Elias –
emailBacterial bioremediation of radionuclides and elucidation of biochemical pathways in subsurface bacteria.
David W. Emerich –
emailEnzymology, physiology and genomics of biological nitrogen fixation and related metabolic activities.
Dennis B. Lubahn –
emailBiochemical genetics and epigenetics of estrogens and related receptors.
Brian Mooney –
emailProteomics of protein expression and assembly; metabolic engineering.
Scott C. Peck –
emailProteomics of protein phosphorylation and protein kinases; signaling and secretion during host-pathogen interactions.
Thomas P. Quinn –
emailCancer diagnostics, radiopharmaceutical imaging and therapy; cell and molecular imaging.
Frank J. Schmidt –
emailCombinatorial chemistry of RNA and antimicrobial peptides; the prebiotic RNA world.
Gary Stacey (Plant Pathology) –
emailFunctional genomics of plant-microbe interactions and plant development.
Jay J. Thelen –
emailProteomics and phosphoproteomics of seed development in oil seeds.
Judy D. Wall –
emailEnvironmental microbiology; bioremediation of toxic metal; genetics and biochemistry of sulfate-reducing bacteria.
return to top Receptors & Signaling
Susan L. Deutscher –
emailCombinatorial biology applied to cancer detection and therapy.
Laurie Erb –
emailMolecular studies of nucleotide receptors.
William R. Folk –
emailGene expression and DNA replication of DNA tumor viruses; plant biotechnology and medical use.
Thomas Guilfoyle –
emailTranscriptional control by auxins in plants; plant RNA polymerases.
Mark Hannink –
emailThe BTB-Kelch substrate adaptor family in development, oncogenesis and neurodegeneration.
Gerald Hazelbauer –
emailTransmembrane receptors and sensory transduction in bacterial chemotaxis.
Antje Heese –
emailMembrane trafficking in plant innate immunity.
Dennis B. Lubahn –
emailBiochemical genetics and epigenetics of estrogens and related receptors.
Jan A. Miernyk (USDA) –
emailProtein targeting and folding in plants, organelle biogenesis, posttranslational modifications.
Scott C. Peck –
emailProteomics of protein phosphorylation and protein kinases; signaling and secretion during host-pathogen interactions.
Michael J. Petris –
emailThe regulation of metal nutrition and impacts on common human diseases.
R. Michael Roberts (Animal Science) –
emailReproductive biology: signaling between conceptus and uterus; stem cells.
Cheikh Seye –
emailNucleotide receptor signaling and cardiovascular disease.
Agnes Simonyi –
emailGlutamate receptors in learning and memory; ischemic induction of inflammatory factors and treatment with polyphenols.
Grace Y. Sun –
emailNeurodegenerative diseases, Signal transduction, phospholipases A2, oxidative stress, anti-inflammatory and anti-oxidant botanical compounds
Chun Tang –
emailSpatial and temporal characterization of macromolecular dynamics involved in protein complexes and signaling pathways
Richard Tsika –
emailTranscriptional regulation in striated muscle during development, activity, and stress; transgenic mouse models.
Steven R. Van Doren –
emailStructural biology: NMR investigations of protein structure, dynamics and protein-protein interactions, particularly proteins important in inflammatory diseases.
Gary A. Weisman –
emailNucleotide receptors and signaling in inflammation, cardiovascular and autoimmune exocrine disease.
Shuqun Zhang –
emailMAP kinases and signaling in plant defense responses.
return to top Structural and Chemical Biology
Lesa J. Beamer –
emailStructural biology: X-ray crystallography of medically important proteins.
Donald H. Burke (Molecular Microbiology & Immunology) –
emailRibozyme mechanism and evolution and the Origin of Life; antiviral nucleic acid aptamers and the molecular basis of drug resistant HIV-1.
Shi-jie Chen (Physics) –
emailPredicting RNA structures and structural changes; Computational studies of RNA thermal stability and folding kinetics.
Susan L. Deutscher –
emailCombinatorial biology applied to cancer detection and therapy.
Kent Gates (Chemistry) –
emailMechanisms of DNA damage by synthetic and naturally occurring antitumor agents, toxins, and mutagens.
Gerald Hazelbauer –
emailTransmembrane receptors and sensory transduction in bacterial chemotaxis.
Michael Henzl –
emailBiophysical characterization of EF-hand calcium-binding proteins; protein-ligand interactions.
Thomas P. Mawhinney –
emailCarbohydrates in cancer and bacterial infection; cancer prevention and treatment; host-pathogen interactions in cystic fibrosis; analytical methodologies.
Brenda A. Peculis –
emailRNA processing, RNA stability, RNA turnover, RNA decapping enzymes, snoRNPs required for ribosome biogenesis.
Thomas P. Quinn –
emailCancer diagnostics, radiopharmaceutical imaging and therapy; cell and molecular imaging.
Linda RandallMolecular chaperones in protein export; analysis of protein-protein interactions.
Frank J. Schmidt –
emailCombinatorial chemistry of RNA and antimicrobial peptides; the prebiotic RNA world.
Chun Tang –
emailSpatial and temporal characterization of macromolecular dynamics involved in protein complexes and signaling pathways
John J. Tanner (Chemistry) –
emailX-ray crystallography of proline metabolic enzymes, bacterial virulence proteins and anti-DNA antibodies; structural bioinformatics of protein-bound water; molecular dynamics simulations of biological molecules.
Peter A. Tipton –
emailMechanistic enzymology applied to agriculturally and medically important enzymes.
Steven R. Van Doren –
emailStructural biology: NMR investigations of protein structure, dynamics and protein-protein interactions, particularly proteins important in inflammatory diseases.
Wynn A. Volkert (Radiology) –
emailRadiopharmaceuticals for therapy and imaging; nuclear medicine.
Xiaoqin Zou –
emailProtein-ligand interactions, computer-aided drug design and modeling of quantitative structure-function relationships of membrane proteins.
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