Biochemistry

Ribozyme mechanism and evolution and the origin of life; antiviral nucleic acid aptamers and the molecular basis of drug resistant HIV-1.

RNA biochemistry, single molecule fluorescence, NMR, RNA folding and dynamics.

Enzymology, physiology and genomics of biological nitrogen fixation and related metabolic activities.

BTB-Kelch substrate adaptor family in development, oncogenesis and neurodegeneration.

Transmembrane receptors and sensory transduction in bacterial chemotaxis.

Biochemical genetics and epigenetics of estrogens and related receptors.

Protein targeting and folding in plants, organelle biogenesis, posttranslational modifications.

RNA processing, RNA stability, RNA turnover, RNA decapping enzymes, snoRNPs required for ribosome biogenesis.

Regulation of metal nutrition and impacts on common human diseases.

Nitrogen and nitric oxide metabolism in plants.

Metabolism, signal transduction, protein kinases and phosphorylated proteins in plants.

Molecular mechanisms of drug resistance and inhibition of HIV, SARS, and other viral and bacterial pathogens.

Structure-function of crystallins, role of ocular proteases and molecular basis for cataract development.

Neurodegenerative diseases, signal transduction, phospholipases A2, oxidative stress, anti-inflammatory and anti-oxidant botanical compounds.

X-ray crystallography of proline metabolic enzymes, bacterial virulence proteins and anti-DNA antibodies; structural bioinformatics of protein-bound water; molecular dynamics simulations of biological molecules.

Proteomics and phosphoproteomics of seed development and metabolism in oilseeds.

Mechanistic enzymology applied to agriculturally and medically important enzymes.

Environmental microbiology; bioremediation of toxic metal; genetics and biochemistry of sulfate-reducing bacteria.

Nucleotide receptors and signaling in inflammation, cardiovascular and autoimmune exocrine disease.

RNA biochemistry, single molecule fluorescence, NMR, RNA folding and dynamics.

Gene expression and replication; plant nutritive improvement and medical uses.

Transcriptional control by auxins in plants; plant RNA polymerases.

Control of gene expression by plant growth regulators.

BTB-Kelch substrate adaptor family in development, oncogenesis and neurodegeneration.

Biochemical genetics and epigenetics of estrogens and related receptors.

Transcriptional control in mitochondrial biogenesis and oxidative stress.

Cell-cell interactions in pollen recognition and rejection.

RNA processing, RNA stability, RNA turnover, RNA decapping enzymes, snoRNPs required for ribosome biogenesis.

Regulation of metal nutrition and impacts on common human diseases.

Collagen in inherited and acquired diseases of bone and kidney; matrix metalloproteinases; medical genetics.

Nitrogen and nitric oxide metabolism in plants.

Reproductive biology: signaling between conceptus and uterus; stem cells.

Functional genomics of plant-microbe interactions and plant development.

Transcriptional regulation in striated muscle during development, activity, and stress; transgenic mouse models.

Nucleotide receptors and signaling in inflammation, cardiovascular and autoimmune exocrine disease.

MAP kinases and signaling in plant defense responses.

Structural biology: X-ray crystallography of medically important proteins.

Ribozyme mechanism and evolution and the origin of life; antiviral nucleic acid aptamers and the molecular basis of drug resistant HIV-1.

Predicting RNA structures and structural changes; Computational studies of RNA thermal stability and folding kinetics.

RNA biochemistry, single molecule fluorescence, NMR, RNA folding and dynamics.

Gene expression and replication; plant nutritive improvement and medical uses.

Transcriptional control by auxins in plants; plant RNA polymerases.

BTB-Kelch substrate adaptor family in development, oncogenesis and neurodegeneration.

Transmembrane receptors and sensory transduction in bacterial chemotaxis.

Characterizing the role of vesicular trafficking components in plant innate immunity; PAMP-triggered immune responses; flg22-induced trafficking of FLS2.

Single molecule biophysics.

Cell-cell interactions in pollen recognition and rejection.

Protein targeting and folding in plants, organelle biogenesis, posttranslational modifications.

Proteomics of protein phosphorylation and protein kinases; signaling and secretion during host-pathogen interactions.

RNA processing, RNA stability, RNA turnover, RNA decapping enzymes, snoRNPs required for ribosome biogenesis.

Regulation of metal nutrition and impacts on common human diseases.

Collagen in inherited and acquired diseases of bone and kidney; matrix metalloproteinases; medical genetics.

Molecular chaperones in protein export; analysis of protein-protein interactions.

Molecular mechanisms of drug resistance and inhibition of HIV, SARS, and other viral and bacterial pathogens.

Structure-function of crystallins, role of ocular proteases and molecular basis for cataract development.

Transcriptional regulation in striated muscle during development, activity, and stress; transgenic mouse models.

Structural biology: NMR investigations of protein structure, dynamics and protein-protein interactions, particularly proteins important in inflammatory diseases.

Nucleotide receptors and signaling in inflammation, cardiovascular and autoimmune exocrine disease.

MAP kinases and signaling in plant defense responses.

Protein-ligand interactions, protein-protein interactions, computer-aided drug design and modeling of quantitative structure-function relationships of membrane proteins.

Structural biology: X-ray crystallography of medically important proteins.

Ribozyme mechanism and evolution and the origin of life; antiviral nucleic acid aptamers and the molecular basis of drug resistant HIV-1.

Combinatorial biology applied to cancer detection and therapy.

Gene expression and replication; plant nutritive improvement and medical uses.

Mechanisms of DNA damage by synthetic and naturally occurring antitumor agents, toxins and mutagens.

BTB-Kelch substrate adaptor family in development, oncogenesis and neurodegeneration.

Biophysical characterization of EF-hand calcium-binding proteins; protein-ligand interactions.

Biochemical genetics and epigenetics of estrogens and related receptors.

Transcriptional control in mitochondrial biogenesis and oxidative stress.

Carbohydrates in cancer and bacterial infection; cancer prevention and treatment; host-pathogen interactions in cystic fibrosis; analytical methodologies.

Carbohydrates and cancer.

RNA processing, RNA stability, RNA turnover, RNA decapping enzymes, snoRNPs required for ribosome biogenesis.

Regulation of metal nutrition and impacts on common human diseases.

Collagen in inherited and acquired diseases of bone and kidney; matrix metalloproteinases; medical genetics.

Cancer diagnostics, radiopharmaceutical imaging and therapy; cell and molecular imaging.

Reproductive biology: signaling between conceptus and uterus; stem cells.

Molecular mechanisms of drug resistance and inhibition of HIV, SARS, and other viral and bacterial pathogens.

Combinatorial chemistry of RNA and antimicrobial peptides; the prebiotic RNA world.

Structure-function of crystallins, role of ocular proteases and molecular basis for cataract development.

Neurodegenerative diseases, signal transduction, phospholipases A2, oxidative stress, anti-inflammatory and anti-oxidant botanical compounds.

Mechanistic enzymology applied to agriculturally and medically important enzymes.

Transcriptional regulation in striated muscle during development, activity, and stress; transgenic mouse models.

Structural biology: NMR investigations of protein structure, dynamics and protein-protein interactions, particularly proteins important in inflammatory diseases.

Nucleotide receptors and signaling in inflammation, cardiovascular and autoimmune exocrine disease.

Protein-ligand interactions, protein-protein interactions, computer-aided drug design and modeling of quantitative structure-function relationships of membrane proteins.

Enzymology, physiology and genomics of biological nitrogen fixation and related metabolic activities.

Gene expression and replication; plant nutritive improvement and medical uses.

Transcriptional control by auxins in plants; plant RNA polymerases.

Control of gene expression by plant growth regulators.

Characterizing the role of vesicular trafficking components in plant innate immunity; PAMP-triggered immune responses; flg22-induced trafficking of FLS2.

Cell-cell interactions in pollen recognition and rejection.

Protein targeting and folding in plants, organelle biogenesis, posttranslational modifications.

Proteomics of protein phosphorylation and protein kinases; signaling and secretion during host-pathogen interactions.

Nitrogen and nitric oxide metabolism in plants.

Metabolism, signal transduction, protein kinases and phosphorylated proteins in plants.

Functional genomics of plant-microbe interactions and plant development.

Proteomics and phosphoproteomics of seed development and metabolism in oilseeds.

Structural biology: NMR investigations of protein structure, dynamics and protein-protein interactions, particularly proteins important in inflammatory diseases.

MAP kinases and signaling in plant defense responses.

Ribozyme mechanism and evolution and the origin of life; antiviral nucleic acid aptamers and the molecular basis of drug resistant HIV-1.

Combinatorial biology applied to cancer detection and therapy.

Enzymology, physiology and genomics of biological nitrogen fixation and related metabolic activities.

BTB-Kelch substrate adaptor family in development, oncogenesis and neurodegeneration.

Biochemical genetics and epigenetics of estrogens and related receptors.

Proteomics using advanced mass spectrometry and 2D gel electrophoresis.

Proteomics of protein phosphorylation and protein kinases; signaling and secretion during host-pathogen interactions.

Cancer diagnostics, radiopharmaceutical imaging and therapy; cell and molecular imaging.

Combinatorial chemistry of RNA and antimicrobial peptides; the prebiotic RNA world.

Functional genomics of plant-microbe interactions and plant development.

Proteomics and phosphoproteomics of seed development and metabolism in oilseeds.

Environmental microbiology; bioremediation of toxic metal; genetics and biochemistry of sulfate-reducing bacteria.

Combinatorial biology applied to cancer detection and therapy.

Gene expression and replication; plant nutritive improvement and medical uses.

Transcriptional control by auxins in plants; plant RNA polymerases.

BTB-Kelch substrate adaptor family in development, oncogenesis and neurodegeneration.

Transmembrane receptors and sensory transduction in bacterial chemotaxis.

Characterizing the role of vesicular trafficking components in plant innate immunity; PAMP-triggered immune responses; flg22-induced trafficking of FLS2.

Biochemical genetics and epigenetics of estrogens and related receptors.

Cell-cell interactions in pollen recognition and rejection.

Protein targeting and folding in plants, organelle biogenesis, posttranslational modifications.

Proteomics of protein phosphorylation and protein kinases; signaling and secretion during host-pathogen interactions.

Regulation of metal nutrition and impacts on common human diseases.

Reproductive biology: signaling between conceptus and uterus; stem cells.

Molecular mechanisms of drug resistance and inhibition of HIV, SARS, and other viral and bacterial pathogens.

Glutamate receptors in learning and memory. Ischemic induction of inflammatory factors and treatment with polyphenols.

Neurodegenerative diseases, signal transduction, phospholipases A2, oxidative stress, anti-inflammatory and anti-oxidant botanical compounds.

Structural biology: NMR investigations of protein structure, dynamics and protein-protein interactions, particularly proteins important in inflammatory diseases.

Nucleotide receptors and signaling in inflammation, cardiovascular and autoimmune exocrine disease.

MAP kinases and signaling in plant defense responses.

Structural biology: X-ray crystallography of medically important proteins.

Ribozyme mechanism and evolution and the origin of life; antiviral nucleic acid aptamers and the molecular basis of drug resistant HIV-1.

Predicting RNA structures and structural changes; Computational studies of RNA thermal stability and folding kinetics.

RNA biochemistry, single molecule fluorescence, NMR, RNA folding and dynamics.

Combinatorial biology applied to cancer detection and therapy.

Mechanisms of DNA damage by synthetic and naturally occurring antitumor agents, toxins and mutagens.

Transmembrane receptors and sensory transduction in bacterial chemotaxis.

Biophysical characterization of EF-hand calcium-binding proteins; protein-ligand interactions.

Single molecule biophysics.

Carbohydrates in cancer and bacterial infection; cancer prevention and treatment; host-pathogen interactions in cystic fibrosis; analytical methodologies.

RNA processing, RNA stability, RNA turnover, RNA decapping enzymes, snoRNPs required for ribosome biogenesis.

Cancer diagnostics, radiopharmaceutical imaging and therapy; cell and molecular imaging.

Molecular chaperones in protein export; analysis of protein-protein interactions.

Molecular mechanisms of drug resistance and inhibition of HIV, SARS, and other viral and bacterial pathogens.

Combinatorial chemistry of RNA and antimicrobial peptides; the prebiotic RNA world.

X-ray crystallography of proline metabolic enzymes, bacterial virulence proteins and anti-DNA antibodies; structural bioinformatics of protein-bound water; molecular dynamics simulations of biological molecules.

Mechanistic enzymology applied to agriculturally and medically important enzymes.

Structural biology: NMR investigations of protein structure, dynamics and protein-protein interactions, particularly proteins important in inflammatory diseases.

Protein-ligand interactions, protein-protein interactions, computer-aided drug design and modeling of quantitative structure-function relationships of membrane proteins.