Laurie Erb

Research Associate Professor of Biochemistry

Email:	erbl@missouri.edu
Phone:	(573) 884-2065
Lab:	(573) 882-1708
Fax:	(573) 884-253
Office:	540F Bond Life Sciences Center
Mailing Address:	Biochemistry 540F Bond Life Sciences Center University of Missouri-Columbia Columbia, MO 65211
Research Areas:	Molecular studies of nucleotide receptors.

Educational Background

BS	Drury College	Springfield, Mo.	Chemistry and Biology
MS	University of Missouri	Columbia, Mo.	Biochemistry
PhD	University of Missouri	Columbia, Mo.	Biochemistry

Selected Publications

Erb, L., J. Liu, J. Ockerhausen, Q. Kong, R.C. Garrad, K. Griffin, C. Neal, B. Krugh, L.I. Santiago-Perez, F.A. Gonzalez, H.D. Gresham, J.T. Turner, and G.A. Weisman. 2001. An RGD sequence in the P2Y₂ receptor interacts with α_Vβ₃ integrins and is required for G_o-mediated signal transduction. J Cell Biol. 153:491-501.

Seye, C.I., Q. Kong, L. Erb, R.C. Garrad, B. Krugh, M. Wang, J.T. Turner, M. Sturek, F.A. Gonzalez, and G.A. Weisman. 2002. Functional P2Y₂ nucleotide receptors mediate uridine 5'-triphosphate-induced intimal hyperplasia in collared rabbit carotid arteries. Circulation. 106:2720-6.

Liu, J., Z. Liao, J. Camden, K.D. Griffin, R.C. Garrad, L.I. Santiago-Perez, F.A. Gonzalez, C.I. Seye, G.A. Weisman, and L. Erb. 2004. SH3 binding sites in the P2Y₂ nucleotide receptor interact with Src and regulate activities of Src, Pyk2, and growth factor receptors. J Biol Chem. 279:8212-8.

Seye, C.I., N. Yu, F.A. Gonzalez, L. Erb, and G.A. Weisman. 2004. The P2Y₂ Nucleotide Receptor Mediates Vascular Cell Adhesion Molecule-1 Expression through Interaction with VEGF Receptor-2 (KDR/Flk-1) J. Biol. Chem. 279:35679-86.

Kaczmarek, E., L. Erb, K. Koziak, R. Jarzyna, M.R Wink, O. Guckelberger, J.K. Blusztajn, V. Trinkaus-Randall, G.A. Weisman, S.C. Robson. 2005. Modulation of endothelial cell migration by extracellular nucleotides. Thromb Haemost. 93: 735-42.

Camden, J.M., A.M. Schrader, R.E. Camden, F.A. Gonzalez, L. Erb, C.I. Seye, G.A. Weisman. 2005. P2Y₂ nucleotide receptors enhance α-secretase-dependent amyloid precursor protein processing. J. Biol. Chem. 280:18696-702.

Bagchi, S., Z. Liao, F.A. Gonzalez, N.E. Chorna, C.I. Seye, G.A. Weisman, L. Erb. 2005. The P2Y₂ nucleotide receptor interacts with α_V integrins to activate G_o and induce cell migration. J. Biol. Chem. 280:39050-7.